Narcolepsy & Idiopathic Hypersomnia — ORX750

What taking part involves

A screening visit at our Miami office confirms whether a study is a fit. It is provided at no cost and you are under no obligation to continue.

Who may be able to take part

• Adults 18–65
• Diagnosed with NT1, NT2, or idiopathic hypersomnia
• ESS score ≥ 12
• BMI 17–37 kg/m²
• Washout of narcolepsy/IH medications

Final eligibility is determined at your free screening visit.

About this condition

Narcolepsy and Idiopathic Hypersomnia

Narcolepsy and idiopathic hypersomnia are central disorders of hypersomnolence: conditions in which the brain cannot sustain normal wakefulness, so daytime sleepiness persists no matter how much sleep someone gets. They share a diagnostic pathway and are often studied together.

In narcolepsy, sleep and wake intrude on one another, producing sleep paralysis, vivid dreamlike images at sleep onset and, in type 1, cataplexy. In idiopathic hypersomnia, sleep is typically long and uninterrupted but never refreshing, and waking can be prolonged and difficult. Both are diagnosed with an overnight sleep study followed by a multiple sleep latency test.

Other studies for this condition

If this one is not a fit, another may be. Our coordinators check you against every open protocol, not just the one you applied for.

Registry record

This study is listed in the public registry of clinical studies. The record below is maintained by the study sponsor.

What happens after you apply

1. 1
   Apply Online

   Fill out the short form below — it takes about two minutes and is completely confidential.

2. 2
   Pre-Screening Call

   A bilingual research coordinator calls you within 24 hours to ask brief eligibility questions.

3. 3
   Free Screening Visit

   Visit our Miami office for a no-cost medical evaluation: history, physical exam, and any required tests.

4. 4
   Enroll & Begin

   If eligible, you are officially enrolled and begin the study under direct physician supervision.