Narcolepsy Type 1 — ALKS 2680

What taking part involves

A screening visit at our Miami office confirms whether a study is a fit. It is provided at no cost and you are under no obligation to continue.

Who may be able to take part

• Adults 18–70
• Confirmed NT1 diagnosis (MSLT/PSG)
• BMI 18–40 kg/m²
• Washout of current narcolepsy treatment

Final eligibility is determined at your free screening visit.

About this condition

Narcolepsy Type 1

Narcolepsy type 1 is a lifelong neurological disorder in which the brain cannot reliably hold the boundary between sleep and wakefulness. Its defining features are overwhelming daytime sleepiness and cataplexy — brief episodes of muscle weakness usually triggered by strong emotion such as laughter or surprise. Many people also have vivid dreamlike images as they fall asleep, sleep paralysis, and broken sleep at night.

It follows the loss of hypocretin-producing neurons in the hypothalamus, a small group of brain cells that keep wakefulness stable. Diagnosis is made in a sleep laboratory: an overnight sleep study followed the next day by a multiple sleep latency test, and sometimes by measuring hypocretin in spinal fluid. Symptoms usually begin in adolescence or early adulthood and are often mistaken for ordinary tiredness for years before they are recognized.

Other studies for this condition

If this one is not a fit, another may be. Our coordinators check you against every open protocol, not just the one you applied for.

Registry record

This study is listed in the public registry of clinical studies. The record below is maintained by the study sponsor.

What happens after you apply

1. 1
   Apply Online

   Fill out the short form below — it takes about two minutes and is completely confidential.

2. 2
   Pre-Screening Call

   A bilingual research coordinator calls you within 24 hours to ask brief eligibility questions.

3. 3
   Free Screening Visit

   Visit our Miami office for a no-cost medical evaluation: history, physical exam, and any required tests.

4. 4
   Enroll & Begin

   If eligible, you are officially enrolled and begin the study under direct physician supervision.